Protein Coverage Browser
14,340 distinct human proteins across 6 platforms, counted by UniProtKB/Swiss-Prot entry and listed under 15,128 catalogue entries. One protein can have several entries (isoforms, mass spectrometry protein groups, unreviewed accessions), and 47 entries match no Swiss-Prot human protein. Filter by platform to see coverage and overlap.
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Note (Biognosys TrueDiscovery): TrueDiscovery is an MS-DIA platform without a fixed panel: detectable proteins are study- and workflow-dependent. The list shown here (3,575 proteins) is from Kirsher et al. 2025 (Communications Chemistry, Supplementary Data 8, MS-HAP Depletion arm), a published, matched-cohort head-to-head comparison. It reflects Biognosys's standard depletion workflow and is a conservative lower bound relative to the ~7,000 protein groups Biognosys reports using its higher-depth P2 enrichment workflow; it is not exhaustive.
Seer Proteograph XT: Protein list received directly from Seer (April 2026), reflecting 10,698 protein groups identified at least twice across two independent plasma studies. As with all MS-DIA platforms, detectable proteins remain partially study-dependent.
* Biognosys TrueDiscovery protein list is from Kirsher et al. 2025 (Communications Chemistry, Supplementary Data 8, MS-HAP Depletion arm) and is study-dependent: a conservative lower bound relative to the ~7,000-protein P2 enrichment figure Biognosys reports for its higher-depth workflow. Seer Proteograph XT list received directly from Seer (April 2026; 10,698 protein groups, ≥2 identifications across two independent studies). All other platforms represent full published panel contents.